Anagram & Information om | Engelska ordet AMINOPTERIN

Exempel på hur du använder AMINOPTERIN i en mening

• Sidney Farber, pediatric pathologist, requested Yellapragada Subbarow (a friend and colleague from Harvard Medical School then working at Lederle Laboratories) to supply aminopterin and later amethopterin (methotrexate) to conduct trials on to children with leukemia, a diagnosis that was deemed a "death sentence," in 1948.
• Yellapragada Subbarow, known for the synthesis of the first ever chemotherapeutic drug aminopterin, and subsequently methotrexate.
• 1947: Sidney Farber leads a team of researchers who are the first in the world to attain temporary remissions of acute lymphocytic leukemia, the most common cancer in children, using aminopterin.
• HAT Medium (hypoxanthine-aminopterin-thymidine medium) is a selection medium for mammalian cell culture, which relies on the combination of aminopterin, a drug that acts as a powerful folate metabolism inhibitor by inhibiting dihydrofolate reductase, with hypoxanthine (a purine derivative) and thymidine (a deoxynucleoside) which are intermediates in DNA synthesis.
• Subsequent to the recall, the Animal Health Laboratory at the University of Guelph in Ontario, identified contaminants in some of the recalled food: aminopterin, melamine, and cyanuric acid.
• Antimetabolite aminopterin blocks the cellular biosynthesis of purines and pyrimidines from simple sugars and amino acids.

Förberedelsen av sidan tog: 94,89 ms.