Anagram & Information om | Engelska ordet ANEUPLOID


ANEUPLOID

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Exempel på hur du använder ANEUPLOID i en mening

  • XYY syndrome, also known as Jacobs syndrome, is an aneuploid genetic condition in which a male has an extra Y chromosome.
  • Inflammatory breast cancer is a high-grade aneuploid cancer, with mutations and overexpression of p53, high levels of E-cadherin and abnormal cadherin function.
  • Meiotic errors can lead to aneuploidy in the polar bodies, which, in the majority of cases, produces an aneuploid zygote.
  • Rather than having monosomy, or only one copy, the majority of aneuploid people have trisomy, or three copies of one chromosome.
  • In support of this, a study of aneuploidy in single spermatozoa by whole genome sequencing found that, on average, human sperm cells with aneuploid autosomes exhibit significantly fewer crossovers than normal cells.
  • The underlying cause of aneuploidy remains highly debated; however, entosis is shown to perturb cytokinesis (cytoplasmic division) and trigger the formation of aneuploid cells.
  • The parsimony analyses revealed that aneuploid reduction (n=5 to 4) and polyploidy (n=5 to 10) have evolved at least twice in the genus, whereas the obligately submersed growth habit and hypohydrophily have evolved once.
  • A number of fetal nucleic acid molecules derived from aneuploid chromosomes can be detected including SERPINEB2 mRNA, clad B, hypomethylated SERPINB5 from chromosome 18, placenta-specific 4 (PLAC4), hypermethylated holocarboxylase synthetase (HLCS) and c21orf105 mRNA from chromosome 12.
  • As a general rule for most species all of its members are of the same cytodeme excepting only the infrequent aneuploid aberrants.
  • From here, BAIT enables the identification of SCE events, misoriented contigs in the reference genome, aneuploid chromosomes and modes of sister chromatid segregation.
  • Yet, passage through a multipolar intermediate enriches for merotelic chromosome attachments, leading to chromosome mis-segregation and the rapid generation of aneuploid populations from which tumorigenic cells emerge.


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