Information om | Engelska ordet CALICHEAMICIN

Exempel på hur man kan använda CALICHEAMICIN i en mening

• Various species are sources of aminoglycoside antibiotics with spellings that end with -micin, such as gentamicin, mutamicin, netilmicin, retymicin, sisomicin, verdamicin, calicheamicin, and the recently found turbinmicin.
• The calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, with calicheamicin γ1 being the most notable.
• Esperamcin A1 and the related enediyne calicheamicin are the two most potent antitumor agents known.
• However, recent work by Thorson and coworkers revealed the biosynthesis of the dynemicin enediyne core to be catalyzed by an enediyne polyketide synthase (PKSE) similar to that employed in calicheamicin biosynthesis.
• Isolated in 2003 it is part of the family of 10 member ringed enediyne antitumor antibiotic agents, which includes: namenamicin, esperamicin and, calicheamicin.

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