Synonymer & Information om | Engelska ordet CARDIOLIPIN
CARDIOLIPIN
Antal bokstäver
11
Är palindrom
Nej
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Exempel på hur man kan använda CARDIOLIPIN i en mening
- A sample of blood or cerebrospinal fluid is taken and introduced to the antigen – cardiolipin extracted from bovine muscle or heart.
- identified a human mitochondrial protein, monolysocardiolipin acyltransferase (MLCL AT-1), that is identical in amino acid sequence to the 59-kDa C-terminal end of MTP, linking MTP to the remodeling of cardiolipin from monolysocardiolipin.
- Diphosphatidylglycerol (DPG, otherwise known as cardiolipin) in the presence of calcium is also capable of forming this phase.
- In eukaryotic mitochondria phosphatidylglycerol is converted to cardiolipin by reacting with a molecule of cytidine diphosphate diglyceride in a reaction catalyzed by cardiolipin synthase.
- Phosphatidate phosphatase is up-regulated by CDP-diacylglycerol, phosphatidylinositol (formed from reaction of CDP-diacylglycerol with inositol), and cardiolipin.
- It addition, it has a role in cardiolipin (CL) deacylation, and is required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.
- The molecule's positive charge allows for binding to phospholipids and cardiolipin, both of which can be found as epitopes on the surfaces of pathogens, and its 2nd and 3rd helices are principle players in lysing foreign or infected cells.
- Additionally, TIM14 helps regulate mitochondrial morphology by complexing with prohibitins to perform disphosphoglycerolipid cardiolipin (CL) remodeling.
- These studies have shown that divalent cations play a critical role in the fusion process by binding to negatively charged lipids such as phosphatidylserine, phosphatidylglycerol and cardiolipin.
- identified Ups1 as a yeast LTP that can shuttle phosphatidic acid (PA) between mitochondrial membranes: they showed that effective lipid transfer required the interaction of Ups1 with Mdm35 to convert phosphatidic acid into cardiolipin in the inner membrane.
- Laboratory studies show increased serum lactate and alanine, mitochondrial oxidative phosphorylation defects, abnormal mitochondria, abnormal phosphatidylglycerol and cardiolipin profiles in fibroblasts, and abnormal accumulation of unesterified cholesterol within cells.
- was able to reconstitute trimer and tetramer Complex III/IV supercomplexes from purified complexes isolated from Saccharomyces cerevisiae and exogenous cardiolipin liposomes.
- In 1990, biologists Michael Schlame and Bernd Rustow observed the deacylation of cardiolipin into MLCL, which was then converted back into cardiolipin by a protein using linoleoyl coenzyme A, derived from phosphatidylcholine.
- The first contribution of Roland Douce was the characterization of cardiolipin, the major lipid of the mitochondrial membrane of plants and animals, as phosphatidyl ethanolamine.
- Also cardiolipin, phosphatidylcholine, phosphatidylethanolamine, mono- and dimethylphosphatidylethanolamine and phosphatidylglycerol could be detected.
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