Anagram & Information om | Engelska ordet CISPLATIN

Exempel på hur man kan använda CISPLATIN i en mening

• Ototoxic drugs include antibiotics (such as gentamicin, streptomycin, tobramycin), loop diuretics (such as furosemide), and platinum-based chemotherapy agents (such as cisplatin and carboplatin).
• BEP chemotherapy consisting of bleomycin, etoposide and cisplatin for testicular, ovarian and other cancers.
• Other medications such as the antifungal amphotericin B or the cancer drug cisplatin can also cause long-term hypokalemia.
• Relative to cisplatin, the greatest benefit of carboplatin is its reduced side effects, particularly the elimination of nephrotoxic effects.
• Food and Drug Administration (FDA) approved sodium thiosulfate under the trade name Pedmark to lessen the risk of ototoxicity and hearing loss in infant, child, and adolescent cancer patients receiving the chemotherapy medication cisplatin.
• Food and Drug Administration (FDA) approved pemetrexed for treatment of malignant pleural mesothelioma, a type of tumor of the mesothelium, the thin layer of tissue that covers many of the internal organs, in combination with cisplatin for patients whose disease is either unresectable or who are not otherwise candidates for curative surgery.
• In contrast to other drugs of the platinum-based antineoplastic class of drugs cisplatin and carboplatin, oxaliplatin features the bidentate ligand trans-1,2-diaminocyclohexane in place of the two monodentate ammine ligands.
• Doxorubicin and cyclophosphamide are as emetogenic as cisplatin, and preventive drugs should always be considered.
• TPMT is now listed as a pharmacogenomic biomarker for adverse drug reactions to cisplatin by the FDA.
• Combined with amphotericin B, vancomycin, bacitracin, paromomycin, cyclosporine, kanamycin, cisplatin, bumetanide, etoricoxib, furosemide: Would Increase the possibility of ototoxicity and nephrotoxicity.
• Research performed at MSU has greatly contributed to scientific progress and discoveries related to hybrid corn, homogenized milk, chemotherapy drug cisplatin, and Germanium isotope Ge-60.
• Since he was at a cancer research institute, McGinness' other interests included the role of free radicals in the action and toxicity of the anticancer drugs cisplatin, adriamycin, and bleomycin.
• He was treated with an orchidectomy and with the chemotherapeutic drugs bleomycin, vinblastine and cisplatin, and also had an exploratory operation to identify cancer in his lymph nodes.
• ATR/ChK1 inhibitors can potentiate the effect of DNA cross-linking agents such as cisplatin and nucleoside analogues such as gemcitabine.
• Results of two studies regarding adenocarcinomas have shown matuzumab to be well tolerated in combination with two standard chemotherapies – cisplatin, 5-fluorouracil and leucovorin (PFL) as well as epirubicin, cisplatin and capecitabine (ECX) – as a first line therapy.
• In April 2014, Daiichi Sankyo announced that it was halting a multicenter, randomized, double-blind, placebo-controlled Phase III study investigating nimotuzumab for first-line therapy in patients with unresectable and locally advanced squamous cell lung cancer, due to safety issues in certain patients who received a combination of cisplatin, vinorelbine, radiotherapy, and nimotuzumab.
• A correlation exists between the number of active CYP 2D6 alleles and the number of vomiting episodes by patients who receive treatment with cisplatin and ondansetron or tropisetron.
• Inhibition of STAT5a alone would not effect colorectal cancer cells, but when combined with chemotherapies such as cisplatin, it could increase the chemosensitivity of the cancer cells to the drugs.
• Amifostine, approved by the FDA in 1995, which helps prevent kidney damage in patients undergoing cisplatin and carboplatin chemotherapy.
• RPN2 silencing has been reported to repress tumorigenicity and to sensitize the tumors to cisplatin treatment, which led to the longer survival of NSCLC-bearing mice, suggesting that RPN2 may represent a promising new target for RNAi-based medicine against NSCLC.

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