Information om | Engelska ordet HETEROZYGOTES

Exempel på hur man kan använda HETEROZYGOTES i en mening

• If there are more than two different allelic forms, the frequency for each allele is simply the frequency of its homozygote plus half the sum of the frequencies for all the heterozygotes in which it appears.
• However, because complete dominance causes the phenotypes of homozygote dominants and heterozygotes to be the same, it was not until the advent of molecular genetics from the 1960s onwards that heterozygosity in populations could be measured.
• It can occur by various mechanisms, in particular, when the heterozygotes for the alleles under consideration have a higher fitness than the homozygote.
• Studies also revealed that a transferrin saturation (serum iron concentration ÷ total iron binding capacity) over 60 percent in men and over 50 percent in women identified the presence of an abnormality in iron metabolism (hereditary hemochromatosis, heterozygotes and homozygotes) with approximately 95 percent accuracy.
• Studies also reveal that a transferrin saturation (serum iron concentration ÷ total iron binding capacity) over 60 percent in men and over 50 percent in women identified the presence of an abnormality in iron metabolism (hereditary hemochromatosis, heterozygotes and homozygotes) with approximately 95 percent accuracy.
• Serum ferritin concentration is likely to be high in persons with Q248H (mostly heterozygotes) than in wild-type SLC40A1.
• Sickling and sickle cell disease also confer some resistance to malaria parasitization of red blood cells, so that individuals with sickle-cell trait (heterozygotes) have a selective advantage in environments where malaria is present.
• Identifying dominance and co-dominance with a marker may help identify heterozygotes from homozygotes within the organism.
• Since such mutations are viable only in heterozygotes, they cannot be stably maintained through successive generations and therefore continually lead to production of wild-type organisms, which can be prevented by replacing the homologous wild-type chromosome with a balancer.
• However they noted that homozygotes may have less mottling or a slightly lighter hair color than heterozygotes.
• Interestingly, homozygotes and heterozygotes were able to be distinguished in one study through both plasma and urinary levels of cystathionine.
• Furthermore, some heterozygotes may become PROP supertasters (despite a lack of two PAV alleles), indicating overlap between PROP bitterness levels and varying TAS2R38 genotypes.
• Mutations that inactivate a CaSR gene cause familial hypocalciuric hypercalcemia (FHH) (also known as familial benign hypercalcemia because it is generally asymptomatic and does not require treatment), when present in heterozygotes.
• Arion circumscriptus reproduces predominantly by self-fertilization, leading to inbred genetic strains, but the presence of rare heterozygotes demonstrates that mating does occasionally result in outcrossing.
• In a large case–control study performed in Burkina Faso on 4,348 Mossi subjects, that HbC was associated with a 29% reduction in risk of clinical malaria in HbAC heterozygotes and of 93% in HbCC homozygotes.
• Female heterozygotes can also show clinical symptoms due to lyonization (X-inactivation) especially during pregnancy.
• Because of the unusual cruciform pairing configuration in translocation heterozygotes, nondisjunction of homologous centromeres occurs at a measurable but low rate.
• Both mutant and wild-type transthyretin comprise the aggregates because the TTR blood protein is a tetramer composed of mutant and wild-type TTR subunits in heterozygotes.
• When heterozygotes possess a fitness advantage relative to a homozygote, a population with a large number of homozygotes will have a relatively reduced fitness, thus leading to inbreeding depression.
• Homozygotes for a V2A missense mutation in a conserved vertebrate sequence of HES7 resulted in kinked tails while heterozygotes for the mutation presented with moderately kinked tails.

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