Information om | Engelska ordet HOMOZYGOTE

Exempel på hur man kan använda HOMOZYGOTE i en mening

• If there are more than two different allelic forms, the frequency for each allele is simply the frequency of its homozygote plus half the sum of the frequencies for all the heterozygotes in which it appears.
• As early as 1930 Fisher had discussed a situation where, with alleles at a single locus, the heterozygote is more viable than either homozygote.
• However, because complete dominance causes the phenotypes of homozygote dominants and heterozygotes to be the same, it was not until the advent of molecular genetics from the 1960s onwards that heterozygosity in populations could be measured.
• It can occur by various mechanisms, in particular, when the heterozygotes for the alleles under consideration have a higher fitness than the homozygote.
• Overdominance is a rare condition in genetics where the phenotype of the heterozygote lies outside of the phenotypical range of both homozygote parents, and heterozygous individuals have a higher fitness than homozygous individuals.
• If a person carries haplotypes -A-B- and -A-b- then they can only make 2 DQ (AB and Ab), but if a person carries haplotypes -A-B- and -A-B- then they can only make DQ isoform AB, called a double homozygote.
• Individuals who are heterozygote carriers are therefore at increased risk of similar pleiotropic disorders as homozygote carriers afflicted with CS.
• The heterozygote or Light Green/yellowface I with one Yellowface I allele and one wild-type allele is visibly indistinguishable from a Light Green, and the homozygote with two Yellowface I alleles is visibly indistinguishable from a Skyblue.
• The mutation of the same name produces a belly spot and interspersed white hairs on the dorsal aspect of the coat in the heterozygote (W/+) and black-eyed white in the homozygote (W/W).
• Allelic dropout rate increases when an allele of a heterozygote fails to amplify resulting in identification of a ‘false homozygote.
• Many of her genetic experiments led to her and William Bateson defining important terms like "allelomorphs" (nowadays referred to as alleles), heterozygote and homozygote.
• When heterozygotes possess a fitness advantage relative to a homozygote, a population with a large number of homozygotes will have a relatively reduced fitness, thus leading to inbreeding depression.
• The CPIC has provided guidelines for implementation of DPYD pharmacogenetics, indicating that homozygote carriers of low-activity variants should be prescribed an alternative drug, while heterozygotes should receive half of the normal dose.

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