Anagram & Information om | Engelska ordet IMPORTINS

Exempel på hur man kan använda IMPORTINS i en mening

• Although small molecules can enter the nucleus without regulation, macromolecules such as RNA and proteins require association with transport factors known as nuclear transport receptors, like karyopherins called importins to enter the nucleus and exportins to exit.
• ” The mechanism of this localization currently remains unclear, but it is not RanGTP dependent despite its downfield position from RanGTP activity, as TPX2 in Xenopus laevis egg extracts have been shown to accumulate at the center of microtubule asters (after the addition of centrosomes, taxol, or DMSO) and bind to pure microtubules in the presence of importins.
• Importin-β-like factors are the largest class of NTRs and are classified as importins or exportins based on the direction of cargo transport and their response to the RanGTP gradient across the nuclear envelope.
• Aitchison's work in yeast on nuclear transport mechanisms and the nuclear pore complex has led to insights into structure of the nuclear pore complex, and the discovery of a large family of nuclear transport factors – broadly termed karyopherins (aka importins and exportins).

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