Information om | Engelska ordet KAINIC

Exempel på hur man kan använda KAINIC i en mening

• Kainate receptors, or kainic acid receptors (KARs), are ionotropic receptors that respond to the neurotransmitter glutamate.
• CSF1R agonism during seizures increases neuronal survival whereas neuron-specific Csf1r loss-of-function worsens kainic acid excitotoxicity, suggesting CSF1R signaling in neurons directly protects against seizure-related neuronal damage.
• Erythravine inhibited seizures evoked by bicuculline, pentylenetetrazole, and kainic acid as well as increasing the latency of seizures induced by NMDA.
• For example, kainic acid can lead to status epilepticus in animals as it is a cyclic analog of l-glutamate and an agonist for kainate receptors in the brain which makes it a potent neurotoxin and excitant.
• occidentalis inhibited convulsions during seizures induced by bicuculline, picrotoxin, and kainic acid.
• Studying the action of kainic acid -an epileptogenic agent present in algae – he discovered the animal model of TLE produced by kainic acid that mimicked the main features of TLE including the pattern of damage, the resistance to treatments, and the mechanisms underlying how “seizures beget seizures “ due to the  formation by propagated seizures of distant  seizures foci.
• Acromelic acid A (ACRO A) is a toxic compound that is part of a group known as kainoids, characterized by a structure bearing a pyrrolidine dicarboxylic acid, represented by kainic acid.

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