Anagram & Information om | Engelska ordet LEPTIN

Exempel på hur man kan använda LEPTIN i en mening

• Other hormones that affect lipolysis include leptin, glucagon, epinephrine, norepinephrine, growth hormone, atrial natriuretic peptide, brain natriuretic peptide, and cortisol.
• Previously treated as being hormonally inert, in recent years adipose tissue has been recognized as a major endocrine organ, as it produces hormones such as leptin, estrogen, resistin, and cytokines (especially TNFα).
• Prominent faculty members include Nobel Prize laureates Richard Axel, Eric Kandel, and Joachim Frank; author Oliver Sacks; 2011 Pulitzer Prize winner for nonfiction Siddhartha Mukherjee; and Rudolph Leibel whose co-discovery of the hormone leptin, and cloning of the leptin and leptin receptor genes, has had a major role in the area of understanding human obesity.
• Findings in the area of obesity research include the role of the hormone leptin in causing/preventing obesity, how leptin resistance occurs and can be reversed, how a high-fat diet during pregnancy affects the foetus, how the natural hormone PYY can cause limited weight loss, and how reduced caloric intake may slow aging and weakening of the immune system.
• The connection is not well understood, but it is hypothesized that elevated body weight results in higher circulating levels of tryptophan, serotonin, and leptin, which in turn reduces impulsivity.
• It is more likely that a complex set of biological and neuroendocrine pathways related to cortisol secretion contribute to central adiposity, such as leptin, neuropeptide y, corticotropin releasing factor and the sympathetic nervous system.
• At an intraperitoneal dose of 30 milligrams per kilogram, it has been shown to inhibit feeding and induce dramatic weight loss in mice by a mechanism similar to, but independent or downstream of, leptin signaling.
• The dorsomedial hypothalamic nucleus (DMH) receives its circadian information from the suprachiasmatic nucleus, both directly and via subparaventricular zone, and senses leptin and other feeding cues, but it is also possible that it contains its own feeding-entrained oscillator (FEO).
• The intermediate portion aids in production of thyroid releasing hormone, somatostatin, leptin, gastrin, and neuropeptide Y.
• In studies of obese mice, Friedman has found that leptin actually restructures the brain, rewiring the neural circuit that controls feeding.
• Female athletes may not menstruate if they have low body fat levels; fat produces the hormone leptin, which induces production of kisspeptin.
• One type of torafugu, 22-seiki fugu (meaning "22nd-century fugu"), has been genetically modified by removing four leptin receptor genes that control appetite.
• Nonshivering thermogenesis, decreased serum leptin levels, fat mobilization, and hyperphagia are all associated adaptations that the Brandt's voles undergoes in cold environments.
• These adaptations include their high resting metabolic rate and non- shivering thermogenesis along with the production of leptin which is a thermogenesis regulatory hormone.
• Adipose tissue is an endocrine organ that secretes numerous protein hormones, including leptin, adiponectin, and resistin.
• In addition to protein, Fructose, a carbohydrate, has impact on fat deposition, plasma insulin, leptin, thyroid, estradiol, and corticosterone levels, lipogenesis, and lipolysis in the adipose tissue of the rat.
• Sleep deprivation increases the level of ghrelin (hunger hormone) and decreases the level of leptin (fullness hormone), resulting in an increased feeling of hunger and a desire for high-calorie foods.
• Saliva contains growth factors such as epidermal growth factor, VEGF, TGF-β1, leptin, IGF-I, lysophosphatidic acid, hyaluronan and NGF, which all promote healing, although levels of EGF and NGF in humans are much lower than those in rats.
• The hypothalamus senses external stimuli mainly through a number of hormones such as leptin, ghrelin, PYY 3-36, orexin and cholecystokinin; all modify the hypothalamic response.
• Neuroendocrine dysregulation: altered signaling of peptides that facilitate communication between the gut, brain and adipose tissue, such as ghrelin, leptin, neuropeptide Y and orexin, may contribute to the pathogenesis of anorexia nervosa by disrupting regulation of hunger and satiety.

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