Definition & Betydelse | Engelska ordet LYSOSOME

Definition av LYSOSOME

1. lysosom

Exempel på hur man kan använda LYSOSOME i en mening

• Besides degradation of polymers, the lysosome is involved in cell processes of secretion, plasma membrane repair, apoptosis, cell signaling, and energy metabolism.
• Acid hydrolases may be nucleases, proteases, glycosidases, lipases, phosphatases, sulfatases and phospholipases and make up the approximately 50 degradative enzymes of the lysosome that break apart biological matter.
• The mucopolysaccharidoses are part of the lysosomal storage disease family, a group of genetic disorders that result when the lysosome organelle in animal cells malfunctions.
• Cell growth occurs when the overall rate of cellular biosynthesis (production of biomolecules or anabolism) is greater than the overall rate of cellular degradation (the destruction of biomolecules via the proteasome, lysosome or autophagy, or catabolism).
• It is caused by an accumulation of glycogen in the lysosome due to deficiency of the lysosomal acid alpha-glucosidase enzyme (GAA).
• In 1930 he developed the technique of cell fractionation, by which he discovered the agent of the Rous sarcoma, as well as components of cell organelles such as the mitochondrion, chloroplast, endoplasmic reticulum, Golgi apparatus, ribosome, and lysosome.
• Water retention, ionic changes, and acidification of the cell damages membrane-bound intracellular structures including the lysosome and peroxisome.
• Phagocytes are an essential component of the host's innate immune system with various antimicrobial defense mechanisms to clear pathogens by oxidative burst, acidification of phagosomes, and fusion of the phagosome and lysosome.
• In Gaucher's disease, the enzyme glucocerebrosidase is nonfunctional and cannot break down glucocerebroside into glucose and ceramide in the lysosome.
• In cell biology, a lumen is a membrane-defined space that is found inside several organelles, cellular components, or structures, including thylakoid, endoplasmic reticulum, Golgi apparatus, lysosome, mitochondrion, and microtubule.
• HEXB is one of the two subunits forming β-hexosaminidase which functions as a glycosyl hydrolase that remove β-linked nonreducing-terminal GalNAc or GlcNAc residues in the lysosome.
• Sulfatases play important roles in the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodelling sulfated glycosaminoglycans in the extracellular space.
• After entrance into the endosomal vesicle, Ebolavirus membrane fuses with the endosomal membrane to release the viral contents into the cytosol before the endosome can fuse with the lysosome.
• In biology, a phagolysosome, or endolysosome, is a cytoplasmic body formed by the fusion of a phagosome with a lysosome in a process that occurs during phagocytosis.
• The peroxisome is an organelle in the cell similar to the lysosome that functions to detoxify the cell.
• It is important in lysosome function and plays a part in processes such as vesicular trafficking, exocytosis and autophagy.
• During normal phagocytosis, bacteria are enclosed by the phagosome, which fuses with the lysosome to become a phagolysosome.
• As a sorting receptor on the cell surface and on the endoplasmic reticulum-Golgi apparatus within the cell, sortilin is involved in the transport of a wide variety of intracellular proteins between the trans-Golgi network, endosome, lysosome, and secretory granules, as well as the plasma membrane.
• The toxin is activated intracellularly, by the low pH of the lysosome into which the entire protein was internalized via the CD22 receptor.
• Cathepsin L1 is a member of the Peptidase C1 (cathepsin) MEROPS family, which plays an important role in diverse processes including normal lysosome mediated protein turnover, antigen and proprotein processing, and apoptosis.

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