Anagram & Information om | Engelska ordet MALDI

Exempel på hur man kan använda MALDI i en mening

• A small fraction of the peptide (usually 1 microliter or less) is pipetted onto a MALDI target and a chemical called a matrix is added to the peptide mix.
• It is similar in character to electrospray ionization (ESI) in that both techniques are relatively soft (low fragmentation) ways of obtaining ions of large molecules in the gas phase, though MALDI typically produces far fewer multi-charged ions.
• Instead, peptide mass fingerprinting (PMF) and matrix-assisted laser desorption/ionization (MALDI) have recently been used to identify the material of bookbindings.
• Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization technique used in mass spectrometry, allowing the analysis of biomolecules (biopolymers such as proteins, peptides and sugars) and large organic molecules (such as polymers, dendrimers and other macromolecules), which tend to be fragile and fragment when ionized by more conventional ionization methods.
• This method of injection works well with pulsed sources such as MALDI but cannot be interfaced to continuous ion sources like electrospray.
• The EI 50, used for relatively small molecules (as opposed to methods like MALDI), ionizes molecules via electron ionization (normally under 70 electronvolt conditions) and then accelerates them through an electric potential.
• This research led to the idea that MALDI surfaces could be derivatized with SEAC devices; the technique was later described by Hutchens and Yip in 1998.
• CovalX developed and patented a technology platform based on mass spectrometry allowing ultra-fast and direct analysis of protein-protein interactions (PPIs) in solution, called High Mass MALDI.
• The two primary methods used for the ionization of protein in mass spectrometry are electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI).
• Consider a real-world example of a MALDI time-of-flight mass spectrometer instrument which is used to produce a mass spectrum of the tryptic peptides of a protein.
• Nowadays, different ionization techniques have been used, including SIMS, MALDI and desorption electrospray ionization (DESI), as well as other technologies.
• As the system adopts the high separation of HPLC, analytes which are in the liquid mobile phase are often ionized by various soft ionization methods including atmospheric pressure chemical ionization (APCI), electrospray ionization (ESI) or matrix-assisted laser desorption/ionization (MALDI), which attains the gas phase ionization required for the coupling with MS.
• Matrix-assisted laser desorption electrospray ionization (MALDESI) was first introduced in 2006 as a novel ambient ionization technique which combines the benefits of electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI).
• Solid-phase analytes are ionized with matrix-assisted laser desorption ionization (MALDI) for large mass molecules or laser desorption ionization (LDI) for molecules with smaller masses.
• Polymers can be fractionated on an analytical scale by size exclusion chromatography (SEC), Matrix-assisted laser desorption/ionization (MALDI) or field flow fractionation (FFF).
• THAP is also used as a matrix in matrix-assisted laser desorption/ionization (MALDI) for the analysis of acidic glycans and glycopeptides in negative ion mode.
• The first breakthrough came with desorption ionisation methods (secondary ionization mass spectrometry - SIMS, matrix-assisted laser desorption ionization - MALDI) a release said.
• The society's annual meeting is held in the first week of September as well as regular special interest group meetings (Lipidomics, MALDI & Imaging, Ambient Ionisation, Environmental & Food Analysis) through the year, in locations throughout the United Kingdom.

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