Synonymer & Information om | Engelska ordet METHYLGLYOXAL

Exempel på hur man kan använda METHYLGLYOXAL i en mening

• The term DNA glycation applies to DNA damage induced by reactive carbonyls (principally methylglyoxal and glyoxal) that are present in cells as by-products of sugar metabolism.
• There are custom-made bee hives among Leptospermum "Manuka bushes" producing Mānuka honey with measurable methylglyoxal content.
• Glutathione reacts with methylglyoxal to give a hemithioacetal, which converted into S--lactoyl-glutathione by glyoxalase I.
• Methylglyoxal is formed from dihydroxyacetone phosphate (DHAP) by the enzyme methylglyoxal synthase, giving off a phosphate group.
• Aminoacetone is then oxidized and deaminated, giving 2-oxopropanal (methylglyoxal), which is in turn oxidized to pyruvate.
• DJ-1/PARK7 and its bacterial homologs: Hsp31, YhbO, and YajL can repair methylglyoxal and glyoxal glycated nucleotides.
• Although aldose reductase can also detoxify methylglyoxal, the glyoxalase system is more efficient and seems to be the most important of these pathways.
• Secondly, glyoxalase ІІ hydrolyses these thiolesters and in the case of methylglyoxal catabolism, produces D-lactate and GSH from S-D-lactoyl-glutathione.
• VAP-1, in particular, catalyzes the oxidative conversion of primary amines (methylamine and aminoacetone) to aldehydes (formaldehyde and methylglyoxal) ammonium and hydrogen peroxide in the presence of copper and quinone cofactor.
• Glyoxal, methylglyoxal, and phenylglyoxal, which all carry the key 1,2-dicarbonyl moiety, all react with free guanines similar to kethoxal, and can be used to probe unpaired guanine bases in structured RNA.
• It acts to reduce levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone, glyoxal, methylglyoxal, and related dicarbonyls.
• Honey that carries the AMHA's Mark of Authenticity must be pure, natural Manuka honey, produced entirely in Australia, and be tested by an independent, approved laboratory to ensure it meets minimum standards of naturally occurring methylglyoxal, dihydroxyacetone, and leptosperin.
• It is an advanced glycation end-product formed from arginine and methylglyoxal through the Maillard reaction.
• Lethal synthesis, or suicide metabolism, is the biosynthesis of a toxin from a precursor which is not itself toxic, such as the synthesis of fluorocitrate from fluoroacetate or the synthesis of methylglyoxal from glycerol.
• Richard's investigations on the nonenzymatic isomerization and elimination reactions of triosephosphates have shed light on the origin of cellular methylglyoxal, a toxic compound that is neutralized by the action of glyoxalase I and II.

Förberedelsen av sidan tog: 219,53 ms.