Information om | Engelska ordet NORADRENERGIC

Exempel på hur man kan använda NORADRENERGIC i en mening

• Cocaethylene increases the levels of serotonergic, noradrenergic, and dopaminergic neurotransmission in the brain by inhibiting the action of the serotonin transporter, norepinephrine transporter, and dopamine transporter.
• That route of signalling increases the rate of noradrenergic activity in the locus ceruleus, and the person becomes more alert and attentive to their environment.
• Orphanin FQ-nociceptin interactions with the basolateral amygdala noradrenergic system in memory consolidation.
• This is consistent with the fact that one form for neuromodulation, the noradrenergic diffuse modulatory system present in the locus coeruleus, is involved in regulating arousal, attention, and sleep-wake cycles.
• Mianserin is closely related to mirtazapine, both chemically and in terms of its actions and effects, although there are significant differences between the two drugs (for example, its higher noradrenergic activity and lower 5-HT3 receptor antagonism).
• Dexmedetomidine induces sedation by decreasing activity of noradrenergic neurons in the locus ceruleus in the brain stem, thereby increasing the downstream activity of inhibitory γ-aminobutyric acid (GABA) neurons in the ventrolateral preoptic nucleus.
• The histaminergic, dopaminergic, serotonergic, noradrenergic, and cholinergic nuclei which the lateral hypothalamic orexin neurons project onto constitute the primary components of the ascending reticular activating system.
• Bancroft (2005) hypothesizes that the noradrenergic neurons of the locus ceruleus in the brain are perpetually inhibitory to penile erection, and that the cessation of their discharge that occurs during rapid eye movement sleep may allow testosterone-related excitatory actions to manifest as nocturnal penile tumescence.
• The notion of an obsessive-compulsive spectrum of disorders goes back at least to Freud, and was framed neurobiologically by Judith Rapaport, Eric Hollander, and others, who found that these conditions responded to serotonergic agents (such as clomipramine) but not to noradrenergic agents (such as desipramine).
• Depression has been associated with impaired neurotransmission of serotonergic (5-HT), noradrenergic (NE), and dopaminergic (DA) pathways, although most pharmacologic treatment strategies directly enhance only 5-HT and NE neurotransmission.
• Setiptiline (brand name Tecipul), also known as teciptiline, is a tetracyclic antidepressant (TeCA) that acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
• Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a synthetic monoaminergic neurotoxin used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain.
• Charney owns patents in dopamine and noradrenergic reuptake inhibitors in the treatment of schizophrenia and in intranasal administration of ketamine to treat depression.
• It is not uncommon for SSRIs to cause or worsen insomnia; the sedating noradrenergic and specific serotonergic antidepressant (NaSSA) antidepressant mirtazapine (Zispin, Remeron) can be used in such cases.
• The sleep-promoting neurons are believed to project GABA type A and galanin, two known inhibitory neurotransmitters, to arousal-promoting neurons, such as histaminergic, serotonergic, orexinergic, noradrenergic, and cholinergic neurons (neurons mentioned above).
• Noradrenergic cell group A4 is a group of cells exhibiting noradrenergic fluorescence that, in the rat, are located in the Tegmen ventriculi quarti (roof of the fourth ventricle) ventral to the cerebellar nuclei, and in the macaque, are found at the edge of the lateral recess of the fourth ventricle caudally, extending to beneath the floor of the ventricle where they merge with the noradrenergic group A6, the locus ceruleus.
• The pathways in which information reaches the brain and causes GnRH release are not understood well; however, midbrain and brainstem noradrenergic neurones appear to be activated in response to intromission during mating.
• Experimental medicine studies by Husain's group using the dopamine agonist rotigotine and the noradrenergic agonist guanfacine demonstrated that these drugs can ameliorate hemispatial neglect to some extent by improving attention.
• Examples of monoamine neurotoxins include the serotonergic neurotoxins para-chloroamphetamine (PCA), methylenedioxymethamphetamine (MDMA), and 5,7-dihydroxytryptamine (5,7-DHT); the dopaminergic neurotoxins oxidopamine (6-hydroxydopamine), MPTP, and methamphetamine; and the noradrenergic neurotoxins oxidopamine and DSP-4.

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