Synonymer & Anagram | Engelska ordet OLIGO

Exempel på hur man kan använda OLIGO i en mening

• A Morpholino, also known as a Morpholino oligomer and as a phosphorodiamidate Morpholino oligomer (PMO), is a type of oligomer molecule (colloquially, an oligo) used in molecular biology to modify gene expression.
• An organism which has been treated with a morpholino antisense oligo to temporarily knock down expression of a targeted gene is called a morphant.
• Perform microarray experiments — DNA microarray with oligo and cDNA primers, SNP arrays, protein arrays, etc.
• One exon-skipping drug was approved in 2016, by the US FDA: eteplirsen (ExonDys51), a Morpholino oligo from Sarepta Therapeutics targeting exon 51 of human dystrophin.
• Two adaptors were involved: one containing an EcoP15I recognition site and an AC overhang; the other containing a GT overhang, a biotinylated thymine, and an oligo barcode.
• After that, it undergoes enzymatic permeabilization, so that RNA molecules can diffuse down to the slide, with further hybridization of polyadenylated mRNA molecules to the oligo (dT) probes.
• Reverse transcription can be performed with oligo dT primers, barcoded oligo dT primers, or template-switching oligos.

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