Synonymer & Information om | Engelska ordet PHOSPHATIDYLSERINE


PHOSPHATIDYLSERINE

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Exempel på hur du använder PHOSPHATIDYLSERINE i en mening

  • Lecithins are mixtures of glycerophospholipids including phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, and phosphatidic acid.
  • Purified vesicles have a protein:phospholipid ratio of 1:3 with a lipid composition of 40% phosphatidylcholine, 32% phosphatidylethanolamine, 12% phosphatidylserine, 5% phosphatidylinositol, and 10% cholesterol.
  • For example, in human erythrocytes the cytosolic side (the side facing the cytosol) of the plasma membrane consists mainly of phosphatidylethanolamine, phosphatidylserine, and phosphatidylinositol.
  • He also discovered that the amino phospholipids, phosphatidylethanolamine and phosphatidylserine, are inaccessible from outside the cell and proposed therefore that the bilayer is asymmetrical — with choline lipids forming the outer monolayer and the amino lipids the cytoplasmic monolayer.
  • Phagocytic white blood cells recognize apoptotic cells by their exposure of negatively charged phospholipids (phosphatidylserine) on the cell surface.
  • The loss of asymmetry, in particular the appearance of the anionic phospholipid phosphatidylserine on the exoplasmic face, can serve as an early indicator of apoptosis and as a signal for efferocytosis.
  • In flow cytometry, annexin V is commonly used to detect apoptotic cells by its ability to bind to phosphatidylserine, a marker of apoptosis when it is on the outer leaflet of the plasma membrane.
  • Other lipids found commonly in surfactant include phosphatidylglycerol (PG), phosphatidylinositol (PI), phosphatidylethanolamine (PE), and phosphatidylserine (PS).
  • The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another.
  • Other names in common use include phosphatidylserine synthase, CDPdiglyceride-serine O-phosphatidyltransferase, PS synthase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol, (CDPdiglyceride):L-serine O-phosphatidyltransferase, phosphatidylserine synthetase, CDP-diacylglycerol-L-serine O-phosphatidyltransferase, cytidine diphosphoglyceride-serine O-phosphatidyltransferase, CDP-diglyceride-L-serine phosphatidyltransferase, CDP-diglyceride:serine phosphatidyltransferase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine, O-phosphatidyltransferase, and CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase.
  • Key ingredients: N-Acetyle-Cysteine, Vitamin E as Mixed tocopherols, Zinc Picolinate, Soy phosphatidylserine, Ginkgo biloba.
  • The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another.
  • These studies have shown that divalent cations play a critical role in the fusion process by binding to negatively charged lipids such as phosphatidylserine, phosphatidylglycerol and cardiolipin.
  • Studies have shown that antibodies against phosphatidylserine, phosphatidylcholine, phosphatidylglycerol, phosphatidylinositol and phosphatidylethanolamine target the pre-embryo.
  • In the same study administration of proadifen was demonstrated to produce time- and dose-dependent phosphatidylserine externalization, caspase-3 activation and PARP cleavage.
  • Apoptotic events such as membrane blebbing, phosphatidylserine flips (exposure to extracellular space), mitochondrial swelling, and microvesicle shedding are present, but cellular death does not occur.
  • The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another.
  • On a viable cell, phosphatidylserine is only present in the inner layer of the cell membrane – this is maintained by aminophospholipid translocase.
  • Phagocytosis of such cells requires specific receptors on the phagocyte that recognise either phosphatidylserine directly or opsonins bound to the phosphatidylserine or other "eat-me" signals, such as calreticulin.
  • antioxidants, such as resveratrol (Japanese knotweed), which protects against free radical damage and beta-amyloid deposits, N-acetyl cysteine (NAC), phosphatidylserine and apoaequorin,.


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