Synonymer & Information om | Engelska ordet RESTENOSIS

Exempel på hur man kan använda RESTENOSIS i en mening

• Specifically, through the injection of a liquid radiocontrast agent and illumination with X-rays, angiocardiography allows the recognition of occlusion, stenosis, restenosis, thrombosis or aneurysmal enlargement of the coronary artery lumens; heart chamber size; heart muscle contraction performance; and some aspects of heart valve function.
• Morpholinos have been tested for a wide range of applications including prevention of cardiac restenosis after angioplasty, treatment of coronary artery bypass grafts, treatment of polycystic kidney disease, redirection of drug metabolism, treatment of some mutations causing Duchenne muscular dystrophy (DMD), and inhibition of infectious diseases.
• Turbulent flow in the arterial tree can cause a number of concerning effects, including atherosclerotic lesions, postsurgical neointimal hyperplasia, in-stent restenosis, vein bypass graft failure, transplant vasculopathy, and aortic valve calcification.
• The stent slowly releases a drug to prevent the growth of scar tissue and new obstructive plaque material which caused the original blood vessel stenosis, this clogging of a stent is termed restenosis.
• In interventional cardiology, phosphorylcholine is used as a synthetic polymer-based coating, applied to drug-eluting stents, to prevent the occurrence of coronary artery restenosis.
• Rovelizumab was also being tested for treating heart attack, multiple sclerosis, and stroke, and was being explored as a treatment for cerebral vasospasm, head trauma, kidney transplantation, and restenosis.
• Rosmarinic acid methyl ester is a plant-derived Cdk2 inhibitor, which was shown to suppress proliferation of vascular smooth muscle cells and to reduce neointima formation in mouse restenosis model.
• With the high use of intracoronary stents during PCI procedures, the focus of treatment changed from procedural success to prevention of recurrence of disease in the treated area (in-stent restenosis).
• Levitzki also showed that PDGFR kinase inhibitors (PDGFR directed tyrphostins), released from nanoparticles or from a drug eluting stent can be used to inhibit restenosis after balloon angioplasty.
• However, in some cases the dual antiplatelet therapy may be insufficient to fully prevent clots that may result in stent thrombosis; these clots and cell proliferation may sometimes cause standard (“bare-metal”) stents to become blocked (restenosis).
• List of the diseases : gastrointestinal stromal tumor (GIST) (for this disease and the ductal carcinomas, the expression levels are to correlate with necrosis in situ), myeloid leukemia (chronic (CML) and acute (AML) forms), lymphoma, breast cancer, glial brain tumors, colon neoplasia, epidermoid carcinoma, cervical cancer, ovarian cancer, papillary thyroid cancer, pulmonary cancer, atherosclerosis, restenosis.
• 1990s:  Demonstrating that acute coronary events arise from small plaques, explaining their unpredictability, and developing diagnostic MRI imaging to characterize these “vulnerable  plaques” and inhibiting post coronary angioplasty (PCI) fibrosis in pigs by Rapamycin, prompting the introduction of drug-eluting stents (DES) to prevent PCI restenosis.
• However, there are complications associated with stent use, development of thrombosis which impedes the efficiency of coronary stents, haemorrhagic and restenosis complications are problems associated with stents.
• After promising results in three small clinical trials, tranilast was studied in a major clinical trial (the PRESTO trial) by SmithKline Beecham in partnership with Kissei for prevention of restenosis after percutaneous transluminal coronary revascularization, but was not found effective for that application.
• His current research interests include brachytherapy for restenosis prevention bioabsorbable/ biodegradable stents, HDL therapy, intracoronary imaging, valvular heart disease and catheter-based treatment of renal denervation.
• Neointimal hyperplasia is the major cause of restenosis after percutaneous coronary interventions such as stenting or angioplasty.
• In 1968, Lapidot used this principle in piglets to show that a flap of thyroid cartilage rotated on perichondrium to replace a segment of resected cricoid cartilage could survive, suggesting that laryngeal growth could continue after reconstruction without restenosis.

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