Definition, Betydelse, Synonymer & Anagram | Engelska ordet SERINE

Definition av SERINE

1. (biokemi) aminosyran serin

Exempel på hur du använder SERINE i en mening

• It is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyzes proteins.
• Tyrosine kinases belong to a larger class of enzymes known as protein kinases which also attach phosphates to other amino acids such as serine and threonine.
• Threonine sidechains are often hydrogen bonded; the most common small motifs formed are based on interactions with serine: ST turns, ST motifs (often at the beginning of alpha helices) and ST staples (usually at the middle of alpha helices).
• For example, the amino acids serine, cysteine, and selenocysteine are all isoelectronic to each other.
• The β subunits catalyze the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction.
• The gene localizes to a chromosomal region containing several closely related serine protease inhibitors (serpins).
• A variety of syntheses of lanthionine have been published including sulfur extrusion from cystine, ring opening of serine β-lactone, and hetero-conjugate addition of cysteine to dehydroalanine.
• For superfamilies, P: superfamily, containing a mixture of nucleophile class families, S: purely serine proteases.
• Granzyme B (GrB), serine protease most commonly found in the granules of NK cells and cytotoxic T cells.
• Upon uptake into the target organism, it binds irreversibly to the serine residue in the active catalytic site of the cholinesterase enzyme.
• Ghrelin only becomes active when caprylic (octanoic) acid is linked posttranslationally to serine at the 3-position by the enzyme ghrelin O-acyltransferase (GOAT) to form a proteolipid.
• However, these conditions are so vigorous that some amino acids (serine, threonine, tyrosine, tryptophan, glutamine, and cysteine) are degraded.
• The target amino acid is most often serine, threonine, or tyrosine residues (mostly in eukaryotes), or aspartic acid or histidine residues (mostly in prokaryotes).
• The splicing junction of the precursor protein is mainly a cysteine or a serine, which are amino acids containing a nucleophilic side chain.
• However, the catalytic triad tyrosine, lysine, and serine, as well as serine, lysine, serine have been proposed.
• A kallikrein is a type of serine protease, which cleaves peptide bonds after certain amino acids in a protein.
• Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues.
• Eight unphosphorylated repeats of arginine and serine in the RS domain take a helical form with arginine on the outside to reduce charge and in a phosphorylated state, the eight repeats of arginine and serine form a 'claw' shape.
• All mucins contain a tandem repeat domain that has repeating amino acid sequences high in serine, threonine and proline.
• C3 convertase (C4bC2b, formerly C4b2a) belongs to family of serine proteases and is necessary in innate immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis.

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