Anagram & Information om | Engelska ordet TRAS

Exempel på hur man kan använda TRAS i en mening

• The program promotes retraining since workers receive the TRAs only if they participate in a full-time TAA training (or are under a waiver).
• The loss of Aire (Autoimmune regulator) expressing mTECs also causes global loss of tissue restricted antigens (TRAs) and Aire-dependent mimetic cell populations, with the loss of TRAs eventually leading to breakdown of immune tolerance.
• Thus, mTECs are capable to present self-generated TRAs on their MHC molecules to select potential autoreactive T cells.
• These processes are mediated especially by unique subset of stromal cells called Medullary thymic epithelial cells (mTECs) via presentation of Tissue restricted antigens (TRAs) that represent self tissues from almost all parts of the body.
• Antigen-presenting cells (APCs) of the thymus, namely medullary thymic epithelial cells (mTECs), dendritic cells (DCs) and B cells are capable to present peptides derived from TRAs to developing T cells (thymus is the major origin of T cell development) and hereby test, whether their T cell receptors (TCRs) engage self entities and therefore their occurrence in the body can potentially lead to the development of autoimmune disease.

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