Information om | Engelska ordet VINDOLINE

Exempel på hur man kan använda VINDOLINE i en mening

• Vinblastine and vincristine, chemotherapy medications used to treat several types of cancers, are found in the plant and are biosynthesised from the coupling of the alkaloids catharanthine and vindoline.
• is the source for a number of important natural products, including catharanthine and vindoline and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine and vincristine, all of which can be obtained from the plant.
• Tabersonine is the first intermediate leading to the formation of vindoline one of the two precursors required for vinblastine biosynthesis.
• The metabolite is an intermediate in the formation of vindoline, a precursor needed for formation of the pharmaceutically valuable vinblastine and vincristine.
• It is a substrate for deacetylvindoline O-acetyltransferase (DAT) which acetylates a hydroxy group to form vindoline, one of the two immediate precursors for the formation of the pharmacetucially valuable bisindole alkaloid vinblastine.
• The precursor of catharanthine and vindoline is strictosidine, the common precursor of all indole alkaloids.

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