Information om | Engelska ordet A-DNA

Z-DNA is thought to be one of three biologically active double-helical structures along with A-DNA and B-DNA.
A-DNA and Z-DNA differ significantly in their geometry and dimensions to B-DNA, although still form helical structures.
In this model, ATP hydrolysis is used to drive protein conformational changes that alternatively dehydrate and rehydrate the DNA, cyclically driving it from B-DNA to A-DNA and back again.
A-DNA is thought to be one of three biologically active double helical structures along with B-DNA and Z-DNA.
Harvey, "The Scrunchworm Hypothesis: Transitions Between A-DNA and B-DNA Provide the Driving Force for Genome Packaging in Double-Stranded DNA Bacteriophages," J Struct Biol 189:1-8 (2015).
The creation of genomic A-DNA is caused by an interaction with major capsid protein (MCP) dimers, which, during virion assembly, cover pre-genomic B-DNA to form a helical nucleoprotein complex containing genomic A-DNA.

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