Anagram & Information om | Engelska ordet TROPANE

Exempel på hur du använder TROPANE i en mening

• Scopolamine, also known as hyoscine, or Devil's Breath, is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness and postoperative nausea and vomiting.
• Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery.
• The pharmacologically active ingredients of Atropa species include atropine, scopolamine, and hyoscyamine, all tropane alkaloids having anticholinergic, deliriant, antispasmodic and mydriatic properties.
• Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin.
• Brugmansia species are among the most toxic of ornamental plants, containing tropane alkaloids of the type also responsible for the toxicity and deliriant effects of both jimsonweed and the infamous deadly nightshade.
• If passed in its current text (as of May 14, 2017), this bill would schedule a large number of novel psychoactive substances, including 96 phenethylamines, 94 cannabimimetic agents, 15 arylcyclohexylamines, 21 tryptamines, 8 benzylpiperazines, 4 benzodiazepines, 4 opioid or opioid-like substances, 8 piperazines, and 2 tropane alkaloids.
• The main antidote to Calabar bean poisoning is the slightly less toxic tropane alkaloid atropine, which may often succeed; and the other measures are those usually employed to stimulate the circulation and respiration.
• All parts of Datura plants are toxic, containing dangerous levels of tropane alkaloids (hyoscyamine, hyoscine) The main observed effects of ingestion are enlarged pupils, dry mouth, trouble breathing, blurred vision, hallucinations, panic, death.
• Extracts of atropa have been used for poisoning since antiquity, as the plant and its fruits contain tropane alkaloids (primarily hyoscyamine and scopolamine).
• Because mandrakes contain deliriant hallucinogenic tropane alkaloids (atropine, scopolamine, and hyoscyamine) which cause delirium and hallucinations, However, the so-called "mandrakes" used in this way are not always species of Mandragora let alone Mandragora officinarum; for example, Bryonia alba, the English mandrake, is explicitly mentioned in some sources.
• Later, it was found that the same medicine could be used in the production of the tropane alkaloid drugs, scopolamine and hyoscyamine, which are useful for eye surgery, and a multi-million dollar industry was built in Queensland based on this substance.
• Quinuclidine is structurally related to DABCO, in which the other bridgehead is also nitrogen, and to tropane, which has a slightly different carbon frame.
• A shrub or small tree to 10 m in height, bearing attractive, magenta-to-red, hummingbird-pollinated flowers, it is extremely poisonous – hallucinogenic (deliriant) in smaller doses – due to tropane alkaloid content and is used by Chilean machi (shamans) of the Mapuche–Huilliche people in traditional medicine, as a poison and to enter trance states.
• In front-bridged analogs the nitrogen lone pairings rigid fixity makes it reside in an equatorial placing for the piperidine ring-part of the tropane nucleus, pointing to the two-carbon & three methylene unit bridgehead; giving the attested front-bridged cocaine analogues preference for SERT over DAT.
• The extremely toxic (to humans), tropane alkaloid-containing shrub Latua pubiflora (family Solanaceae) was used formerly by the Huilliche people of the Los Lagos Region of southern Chile to catch fish in slow-flowing rivers - either alone or in combination with the juice of Drimys winteri (Winteraceae) - the latter being a fish poison in its own right.
• The main feature differentiating phenyltropanes from cocaine is that they lack the ester functionality at the 3-position terminating in the benzene; and thusly the phenyl is attached direct to the tropane skeleton with no further spacer (therefore the name "phenyl"-tropane) that the cocaine benzoyloxy provided.
• With the combination of two potent dopamine transporter (DAT) binding motifs attached to the tropane ring, the p-iodophenyl group at the 3β-position and a pyrrolidine carboxamide at 2β, RTI-229 has extremely high selectivity for the dopamine transporter (2600x and 4600x selective over NET and 5-HTT respectively) and is one of the most DAT-selective compounds in the RTI series.
• Scopine is a tropane alkaloid found in a variety of plants including Mandragora root, Senecio mikanioides (Delairea odorata), Scopolia carniolica, and Scopolia lurida.
• Aposcopolamine (apohyoscine) is a bio-active isolate of Datura ferox and several species of Physochlaina, - plants belonging to the Nightshade family, Solanaceae in which tropane alkaloids are of frequent occurrence, particularly in tribes Datureae and Hyoscyameae.
• Because mandrakes contain deliriant hallucinogenic tropane alkaloids and the shape of their roots often resembles human figures, they have been associated with magic rituals throughout history, including present-day contemporary pagan traditions.

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